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Drug Checking Resources

CDC Stimulant Guide


The guide intends to assist people who interact with people who use stimulants or are interested in understanding issues related to stimulants in their community. This guide answers the common question about stimulants, stimulant use, stimulant overdose, and stimulant overdose prevention developed by harm reduction experts. The answers provided in this guide are to convey essential information to a variety of audiences. The guide does not contain medical advice; it is purely information and should not be referred to in case of emergency.


To access the guide, click HERE.

StreetCheck App

StreetCheck is an innovative community-partnered project at Brandeis University’s Opioid Policy Research Collaborative (OPRC) to develop and standardize sample collection and reporting for community drug checking programs.  The vision of StreetCheck streamlines community illicit drug sample collection through the use of a mobile based application, speeds analysis of the samples, and makes it easier to communicate results back. Download the app, watch a demo, or get more information. 

StreetCheck is available at no cost and can integrate results from any lab performing off-site testing.  If you are doing research about drug checking, StreetCheck has additional data collection options to protect privacy and confidentiality, and approved protocols useful for researchers. Contact us to learn more.       

Community Drug Checking Program Resources

These resources are for organizations that are thinking about or implementing community drug checking.

Manuals, Protocols, and Technical Briefs​​​​ 

This is a brief reference document on common active cuts found in opioids and stimulants when using FTIR.

This is a brief reference document on common inactive cuts found in opioids and stimulants when using FTIR.  ​

This is a brief reference document for using immunoassay test strips for drug checking (FTS, XTS, BTS)

This guide was developed by the MADDS Team to provide guidance on sending samples to external lab partners.

This is a brief reference document for quality control on StreetCheck.

This brief reference document provides guidance and tips for using xylazine test strips for drug checking. 

This brief reference document provides guidance for testing cannabis and blotter paper samples.

Technical Training Videos

In this video we run through the process of using and interpreting BTNX xylazine test strips, along with BTNX fentanyl test strips and DTM cassette style xylazine test strips on a single sample.  

In this video we run through the process of using and interpreting DTM cassette style xylazine test strips 

  • Xylazine Deep Dive (56:43) 

    This video discusses tools and tips for identifying xylazine with OPUS on the FTIR.

  • Inositol Demo (10:27)

    This video is an example of setting up the FTIR, scanning a sample and conducting analysis with the OPUS software.​

Helpful Tools for Talking with Program Participants & Learning About the Drug Supply

       This guide was developed for StreetCheck users to reference when attaching flags to cataloged samples. ​ 

New to Drug Checking or Thinking about Starting a Drug Checking Program?

This video from Drug Policy Alliance provides a snapshot of national and regional drug supply trends from drug checking laboratory data and discusses how harm reduction programs are using this information to help keep communities safe.

This is a resource for folks unfamiliar with drug checking and discusses the how and why we provide drug checking services and ways to talk about it with you program participants.   

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Publications, Reports and Other Resources

Position Statement on Community Drug Checking from AMERSA 

(Association for Multidisciplinary Education and Research in Substance use and Addiction)

Fentanyl Test Strip Kit Distribution Pilot Evaluation Report

Fentanyl Test Strip instructions and Resources

Legislative Analysis and Public Policy Association. 2021. Fentanyl Test Strips Fact Sheet. 

Available at


TC Green, R Olson, C Jarczyk, e Erowid, F Erowid, S Thyssen, R Wightman, B del Pozo, L Michelson, A Consigli, B Reilly, S Ruiz. Implementation and Uptake of the Massachusetts Drug Supply Data Stream: A Statewide Public Health-Public Safety Partnership Drug Checking Program. Journal of Public Health Management and Practice (2022) Nov-Dec 01;28(Suppl 6):S347-S354. DOI: 10.1097/PHH.0000000000001581. PMID: 36194805; PMCID: PMC9531987.

Rachel S. Wightman, Earth Erowid, Fire Erowid, Sylvia Thyssen, Mary Wheeler, Benjamin Pulminskas, Rebecca Olson & Traci C. Green (2021). Confirmed reports of bupropion sold as crack cocaine in the illicit drug supply, Clinical Toxicology, DOI: 10.1080/15563650.2021.1898632

Linktree to Resources and More Information

MDPH Clearinghouse Fentanyl Test Strip Instructions (see image)
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